YOL006C
Bait ORF
Bait gene name TOP1
Bait description Topoisomerase I, nuclear enzyme that relieves torsional strain in DNA by cleaving and re-sealing the phosphodiester backbone; relaxes both positively and negatively supercoiled DNA; functions in replication, transcription, and recombination
Rows with this bait as bait Rows with this bait as bait (1)
Rows with this bait as prey Rows with this bait as prey (0)
Prey ORF
Prey gene name TRI1
Prey description Non-essential sumoylated protein of unknown function with similarity to components of human SWI/SNF complex including SMRD3; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm, nucleus and nucleolus
Rows with this prey as prey Rows with this prey as prey (1)
Rows with this prey as bait Rows with this prey as bait (0)
Literature on bait (YPD) 115
Literature on prey (YPD) 4
Literature shared by bait and prey 4
Literature sharing score 7
CuraGen (0 or 1) 1
S. Fields (0 or 1) 0
Association (0 or 1,YPD) 0
Complex (0 or 1,YPD) 0
Synthetic lethality (0 or 1,YPD) 0
Co-induced by (YPD) -
Co-repressed by (YPD) -
Not affected by(YPD) -
Interologs -
Expression similarity (BRITE) -
Alternative path with 1 intervening protein (YPD) 0
Alternative path with 2 intervening proteins (YPD) 0
IST hit 6
IST hit in the opposite bait/prey orientation -