YHR005C
Bait ORF
Bait gene name GPA1
Bait description GTP-binding alpha subunit of the heterotrimeric G protein that couples to pheromone receptors; negatively regulates the mating pathway by sequestering G(beta)gamma and by triggering an adaptive response; activates Vps34p at the endosome
Rows with this bait as bait Rows with this bait as bait (1)
Rows with this bait as prey Rows with this bait as prey (0)
Prey ORF
Prey gene name STE4
Prey description G protein beta subunit, forms a dimer with Ste18p to activate the mating signaling pathway, forms a heterotrimer with Gpa1p and Ste18p to dampen signaling; may recruit Rho1p to the polarized growth site during mating; contains WD40 repeats
Rows with this prey as prey Rows with this prey as prey (2)
Rows with this prey as bait Rows with this prey as bait (0)
Literature on bait (YPD) 120
Literature on prey (YPD) 133
Literature shared by bait and prey 53
Literature sharing score 409
CuraGen (0 or 1) 0
S. Fields (0 or 1) 0
Association (0 or 1,YPD) 1
Complex (0 or 1,YPD) 1
Synthetic lethality (0 or 1,YPD) 0
Co-induced by (YPD) haploidy
Co-repressed by (YPD) diploidy
Not affected by(YPD) -
Interologs -
Expression similarity (BRITE) -
Alternative path with 1 intervening protein (YPD) 2
Alternative path with 2 intervening proteins (YPD) 4
IST hit 10
IST hit in the opposite bait/prey orientation -